Publication

Xu, G., Mihaylova, T., Li, D., Tian, F., Farrehi, P.M., Parent, J.M., Mashour, G.A., Wang, M.M., Borjigin*, J. Surge of neurophysiological coupling and connectivity of gamma oscillations in the dying human brain. Proc. Natl. Acad. Sci. USA, 2023 May 9;120(19):e2216268120. doi: 10.1073/pnas.2216268120. Epub 2023 May 1. PMID: 37126719. (Pubmed)

Huang, Z., Li, Y., Konishi, K., Sakai, Y., Tashiro, K., Fukami, T., Borjigin*, J. In Vitro deacetylation of N-acetylserotonin by arylacetamide deacetylase. J. Pineal Res. 2023 Mar 31:e12870. doi: 10.1111/jpi.12870. PMID: 37002641. (Pubmed)

Lee, S.J., Kondepudi, A., Young, K.Z., Zhang, X., Cartee, N.M.P., Chen, J., Jang, K.Y., Xu, G., Borjigin, J., Wang*, M.M. Concentration of non-myocyte proteins in arterial media of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. PLoS One, 2023, 18(2):e0281094. doi: 10.1371/journal.pone.0281094. PMID: 36753487; PMCID: PMC9907840. (Pubmed)

Glynos, N.G., Carter, L., Lee, S.J., Kim, Y., Kennedy, R.T., Mashour, G.A., Wang, M.M., Borjigin*, J. Indolethylamine N-methyltransferase (INMT) is not essential for endogenous tryptamine-dependent methylation activity in rats. Scientific Reports, 2023 13(1):280. doi: 10.1038/s41598-023-27538-y. PMID: 36609666; PMCID: PMC9822953. (Pubmed)

Lee, S.J., Zhang, X., Xu, G., Borjigin, J., Wang*, M.M. A midposition NOTCH3 truncation in inherited cerebral small vessel disease may affect the protein interactome. J. Biol Chem, 2023, 299(1):102772. doi: 10.1016/j.jbc.2022.102772. Epub 2022 Dec 5. PMID: 36470429; PMCID: PMC9808000. (Pubmed)

Young KZ, Xu G, Keep SG, Borjigin J, Wang MM. Overlapping Protein Accumulation Profiles of CADASIL and CAA: Is There a Common Mechanism Driving Cerebral Small-Vessel Disease? Am J Pathol. 2021 Nov;191(11):1871-1887. (Pubmed)

Brown DL, Xu G, Belinky Krzyske AM, Buhay NC, Blaha M, Wang MM, Farrehi P, Borjigin J. Electrocardiomatrix Facilitates Accurate Detection of Atrial Fibrillation in Stroke Patients. Stroke. 2019 Jul;50(7):1676-1681. (Pubmed)

Dean JG, Liu T, Huff S, Sheler B, Barker SA, Strassman RJ, Wang MM, Borjigin J. Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DMT) in Mammalian Brain. Sci Rep. 2019 Jun 27;9(1):9333. (Pubmed)

Tian F, Liu T, Xu G, Ghazi T, Sajjad A, Farrehi P, Wang MM, Borjigin J. Surge of Corticocardiac Coupling in SHRSP Rats Exposed to Forebrain Cerebral Ischemia. Journal of Neurophysiology. (2019) Jan 9. doi: 10.1152/jn.00533.2018. (Pubmed)

Xu G, Dodaballapur S, Mihaylova T, Borjigin J. Electrocardiomatrix facilitates qualitative identification of diminished heart rate variability in critically ill patients shortly before cardiac arrest. Journal of Electrocardiology. (2018) 51(6), 955-961. (Pubmed)

Lee V, Xu G, Liu V, Farrehi P, Borjigin J. Accurate detection of atrial fibrillation and atrial flutter using the electrocardiomatrix technique. J Electrocardiol. 2018 Aug 11. pii: S0022-0736(18)30340-6. (Pubmed)

Xu G, Dean J, Liu T, Tian F, Borjigin J. Chronic circadian advance shifts abolish melatonin secretion for days in rats. Neurobiology of Sleep and Circadian Rhythms (2018) Volume 5, June, 78-83. (Link)

Tian F, Liu T, Xu G, Li D, Ghazi T, Shick T, Sajjad A, Wang MM, Farrehi P and Borjigin J. Adrenergic Blockade Bi-directionally and Asymmetrically Alters Functional Brain-Heart Communication and Prolongs Electrical Activities of the Brain and Heart during Asphyxic Cardiac Arrest. (2018) Front. Physiol. 9:99. doi: 10.3389/fphys.2018.00099. (Link)

Wadas, B., Borjigin, J., Huang, Z., Oh, J-H., Hwang, C-S., Varshavsky. Degradation of Serotonin N-Acetyltransferece, a circadian regulator, by the N-end rule pathway (2016), J. Biol. Chem, 291, 17178-17196. (Link)

Li, D., Tian, F., Rengifo, S., Xu, G., Wang, M.M., Borjigin, J. Electrocardiomatrix: A new method for beat-by-beat visualization and inspection of cardiac signals (2015b).  J. Integrative Cardiology, 1(5): 124-128. (Link)

Li, D., Mabrouk, O.S., Liu, T., Tian, F., Xu, G., Rengifo, S., Choi, S.J., Mathur, A., Crooks, C.P., Kennedy, R.T., Wang, M.M., Ghanbari, H., Borjigin*, J. Asphyxia-activated corticocardiac signaling accelerates onset of cardiac arrest (2015a). Proc. Natl. Acad. Sci. USA, pii: 201423936. (Pubmed)

Borjigin*, J., Wang, M.M., Mashour, G.A. Reply to Greyson et al.: Experimental evidence lays a foundation for a rational understanding of near-death experiences (2013). Proc. Natl. Acad. Sci. USA, 110(47):E4406. (Pubmed)

Borjigin*, J., Wang, M.M., Mashour, G.A. Reply to Chawlaand Seneff: Near-death electrical brain activity in humans and animals requiresadditional studies (2013). Proc. Natl. Acad. Sci. USA, 110(44):E4124. (Pubmed)

Borjigin*, J., Lee, U., Liu, T., Pal, D., Huff, S., Klarr, D., Sloboda, J., Hernandez, J., Wang, M.M., Mashour, G.A. Surge of neurophysiological coherence and connectivity in the dying brain (2013). Proc. Natl. Acad. Sci. USA, 110(35):14432-7. (Pubmed)

Wang*, M.M., Lee, S.J., Kim, J., Majersik, J.J., Blaivas, M., Borjigin, J. ABO blood antigens define human cerebral endothelial diversity (2013), Neuroreport, 24(2):79-83. (Pubmed)

Barker*, S.A, Borjigin, J., Lomnicka, I., Strassman, R. LC/MS/MS analysis of the endogenous dimethyltryptamine hallucinogens, their precursors, and major metabolites in rat pineal gland microdialysate. Biomed Chromatogr. 2013 Jul 23. doi: 10.1002/bmc.2981. (Pubmed)

Ahmed, S., Meng, H., Liu, T., Sutton, B., Opp, M.R., Borjigin*, J., Wang, M.M. Ischemic stroke selectively inhibits REM sleep of rats (2011) Exp. Neurology, 232(2):168-75. (Pubmed)

Calinescu, A., Liu, T., Wang, M.M., Borjigin*, J. Transsynaptic activity-dependent regulation of axon branching and neurotrophin expression in vivo (2011) J. Neurosci., 31:12708-12715. (Pubmed)

Huang, Z., Liu, T., Borjigin*, J. N-terminal residues regulate proteasomal degradation of AANAT (2010) J. Pineal Res., Apr;48(3):290-6. (Pubmed)

Kuppala, D., Deng, J., Brewer G.J., Wang, M.M., Borjigin*, J. Wilson disease mutations in the American population: Identification of five novel mutations in ATP7B (2009), The Open Hepatology J., 1:1-4. (Link)

Schwartz, M.D., Wotus, C., Liu, T., Friesen, W.O., Borjigin*, J., Oda*, G.A., de la Iglesia*, H.O. Dissociation of circadian and light inhibition of melatonin release through forced desynchronization in the rat (2009), Proc. Natl. Acad. Sci. USA, 106:17540-17545.  (Pubmed)

Lee, S.J., Liu, T., Chattoraj, A., Zhang, S.L., Wang, L., Lee, T., Wang, M.M., Borjigin*, J. Posttranscriptional regulation of pineal melatonin synthesis in Octodon degus (2009) J. Pineal Res., Aug; 47(1): 75-81. (Pubmed)

Huang, Z., Chattoraj, A., Li, X., Snyder, S.H., Borjigin*, J. The increased degradation of NAT-H28Y mutant protein is due to a reduced interaction with 14-3-3 (2009) J. Pineal Res., Jan; 46: 119-120. (Pubmed)

Meng, H., Liu, T., Borjigin, J., Wang*, M. M. Ischemic stroke destabilizes circadian rhythms (2008) J. Circadian Rhythms, Oct 15; 6(1):9. (Pubmed)

Huang, Z., Liu, T., Chattoraj, A., Ahmed, S., Wang, M.M., Deng, J., Sun, X., Borjigin*, J. Posttranslational regulation of TPH1 is responsible for the nightly surge of 5-HT output in the rat pineal gland (2008) J. Pineal Res., Nov; 45: 506-514. (Pubmed)

Liu, C., Li, S., Liu, T., Borjigin, J., and Lin*, J. Integration of mammalian clock and energy metabolism through transcriptional co-activator PGC-1alpha (2007) Nature, 447: 477-482. (Link)

Liu, T., Borjigin*, J. Relationship between nocturnal serotonin surge and melatonin onset in rodent pineal gland (2006) J. Circadian Rhythms, 4: 1-12. (Pubmed)

Liu, T., Borjigin*, J. Reentrainment of the circadian pacemaker through three distinct stages (2005) J. Biol. Rhythms, 20: 441-450. (Pubmed)

Liu, T., Borjigin*, J. Free Running Rhythms of Pineal Circadian Output (2005) J. Biol. Rhythms, 20: 430-440. (Pubmed)

Ahmed, S., Deng, J., Borjigin*, J. A new strain of rat for functional analysis of PINA (2005) Mol. Brain Res., 137: 63-69. (Pubmed)

Liu, T., Borjigin*, J. N-acetyltransferase is not the rate-limiting enzyme of melatonin synthesis at night(2005), J. Pineal Res., 39: 91-96. (Pubmed)

Huang, ZP., Deng, J., Borjigin*, J. A novel H28Y mutation in LEC rats leads to decreased NAT protein stability in vivo and in vitro (2005), J. Pineal Res., 39: 84-90. (Pubmed)

Ala, A., Brewer, G., Borjigin*, J., Rochwarger, A., Schilsky M., Wilson disease in septuganerian siblings: raising the bar for diagnosis (2005) Hepatology, 41: 668-70. (Pubmed)

Kuberan, B., Lech, M., Borjigin, J., Rosenberg*, R.D. Light induced 3-O-sulfotransferase expression alters pineal heparan sulfate fine structure: A surprising link to circadian rhythm (2004) J. Biol. Chem., 279: 5053-5054. (Pubmed)

Sun, X., Liu, T., Deng, J., Borjigin*, J. Long-term in vivo pineal microdialysis (2003), J. Pineal Res., 35: 1-8. (Pubmed)

Borjigin*, J., Deng, J., Sun, X., De Jesus, M., Liu, T., Wang, M.M. Diurnal pineal 3-o-sulphotransferase 2 expression controlled by beta -adrenergic repression (2003), J. Biol. Chem., 278: 16315-9. (Pubmed)

Sun X., Deng J., Liu T., and Borjigin* J. Circadian 5-HT production regulated by adrenergic signaling (2002), Proc. Natl. Acad. Sci. USA, 99: 4686-4691. (Pubmed)

Borjigin J, Deng J, Wang MM, Li X, Blackshaw S, Snyder* SH. Circadian rhythm of patched1 transcription in the pineal regulated by adrenergic stimulation and cAMP (1999), J. Biol. Chem. 274: 35012-5. (Pubmed)

Borjigin, J., Payne, A.S., Deng, J., Li, X., Wang, M.M., Ovodenco, B., Gitlin, J.D., and Snyder*, S.H. A Novel Pineal Night-Specific ATPase Encoded by the Wilson Disease Gene (1999), J. Neurosci.,19: 1018-1026. (Pubmed)

Li, X., Chen, S., Wang, Q., Zack, DJ, Snyder, SH., and Borjigin*, J. A pineal regulatory element (PIRE) mediates transactivation by the pineal/retina-specific transcription factor CRX (1998) Proc. Natl. Acad. Sci. USA, 95: 1876-1881. (Pubmed)

Foulkes, N.S., Borjigin, J., Snyder*, S.H., and Sassone-Corsi, P. Transcriptional control of circadian hormone synthesis via the CREM feedback loop (1996), Proc. Natl. Acad. Sci. USA, 93: 14140-14145. (Pubmed)

Borjigin, J., Wang, M.M., and Snyder* S.H. Diurnal variation in mRNA encoding serotonin N-acetyltransferase in pineal gland (1995), Nature, 378: 783-785. (Pubmed)

Borjigin, J., Nathans*, J. Insertional mutagenesis as a probe of rhodopsin's topography, stability, and activity (1994), J. Biol. Chem., 269: 14715-14722. (Pubmed)

Borjigin, J., Nathans*, J. Bovine pancreatic trypsin inhibitor-trypsin complex as a detection system for recombinant proteins (1993), Proc. Natl. Acad. Sci. USA, 90: 337-341. (Pubmed)

Borjigin, J., Tease, L.A., Barnes, W., Chan*, W.Y. Expression of the pregnancy-specific Beta1-glycoprotein genes in human testis (1990), Biochem. Biophys. Res. Comm. 166: 622-629. (Pubmed)

Chan, W.Y., Liu, Q.R., Borjigin, J., Busch, H., Rennert, O.M., Tease, L.A., Chan*, P.K. Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth (1989), Biochemistry, 28: 1033-1039. (Pubmed)

Chan, W.Y., Tease, L.A., Borjigin, J., Chan, P .K., Rennert, O.M., Srinivasan, B., Shupert, W.L., Cook*, R.G. Pregnancy-specific Beta 1-glycoprotein mRNA is present in placental as well as non-placental tissues (1988), Human Reproduction 3: 677-685. (Pubmed)

Chan, W.Y., Tease, L.A., Bates, Jr, J.M., Borjigin, J., Shupert*, W.L. Pregnancy-specific Beta 1 protein in rat: Tissue distribution of the mRNA and the identification of testicular cDNA clones (1988), Human Reproduction 3: 687-692. (Pubmed)

Chan, W.Y., Borjigin, J., Zheng, Q.X., Shupert*, W.L. Characterization of cDNA encoding human pregnancy-specific Beta 1-glycoprotein from placenta and extra placental tissues and their comparison with carcinoembryonic antigen (1988), DNA 7: 545-555. (Pubmed)